Grant and Fiona Anderson have been married for forty-four years. Their marriage has been a generally happy and loving one although not perfect due to some indiscretions when Grant was working as a college professor. Fiona has just been admitted to Meadowlake, a long term care facility near their country home in southwestern Ontario, because her recent lapses of memory have been diagnosed as a probable case of Alzheimer's disease. She and Grant made this decision together, although a still lucid Fiona seems to have made peace with the decision and her diagnosis more so than Grant. With respect to the facility, what Grant has the most difficulty with are what he sees as the sadness associated with the facility's second floor - where the more advanced cases are housed - but most specifically the facility's policy of no visitors within the first thirty days of admission to allow the patient to adjust more easily to their new life there...

A businessman sinks $200 million into a special project to help fight brain cancer. As part of this project, medical biologist Susan McAlester rather naughtily figures out a way to genetically enlarge shark brains, so that cancer-battling enzymes can be harvested. However, the shark subjects become super smart and decide they don't much like being cooped up in pens and being stabbed with hypodermics, so they figure a way to break out and make for the open sea...